"Immunopharmacology of Mast Cells and Basophils -The Handbook of Immunopharmacology-(HC)"
      John C. Foreman (ed.)/Academic Press
  1. "Introduction to Mast Cells and Basophils"(John C. Foewman)

  2. "Development of Mast Cells and Basophils"
           (Yukihiko Kitamura, Tsutomu Kasugai, Shintaro Nomura and Hiroshi Matsuda)
    1) Introduction
    2) Development of Mast Cells
       ・Useful Mutant Animals
       ・Culture of Mast Cells
       ・Differenciation Process
       ・Regulation of Developmant
       ・Effect of Microenvironment on Phenotypes
       ・Inhabition of Development
    3) Development of Basophils
       ・Differentiation Process
       ・Regukation of Development
    4) Concluding Remarks
    5) Acknowledements
    6) References

  3. "Mast Cells Heterogeneity"(Kim E. Barrett and Frederick L. Pearce)
    1) Introduction
       ・Definitions and Nomenclature
    2) Mast Cell Growth and Differentiation
       ・Mast Cell Precursors
       ・Mast Cell Growth Factors
       ・Routre to Mast Cell Subpopulations
    3) Expression of Mast Cell Heterogeneity
       ・Histochemical Characteristics
       ・Mediators
       ・Functional Aspects
    4) Implications of Mast Cell Heterogeneity
    5) Acknowledgements
    6) References

  4."The High-Affinity IgE Receptor"(Gottfried Alber and Henry Metzger)
    1) Introduction
    2) The Genes for the Subunits
       ・Chromosomal Localization
       ・Genomic Organization
    3) Receptor Expression
       ・Developmental Aspects
       ・Biosynthesis
       ・Expression of Transfected Receptors
    4) Structure of the Receptor
       ・Individual Subunits
       ・Comparison with Other Fc Receptors
    5) Srtucture-Function Relationships
       ・Interaction with IgE
       ・Receptor Activation
    6) Concluding Remarks
    7) References

  5. "Non-immunological Stimuli of Mast Cells and Basophil Leucocytes"(John C. Foreman)
    1) Introduction
    2) Peptides and Polybasic Components
       ・Compound 48/80
       ・Peptides from the CH4 Domain of IgE
       ・Neuropeptides
       ・Other Peptides
    3) Anaphylatoxins
    4) Interleukins
    5) Dextran
    6) Lectins
    7) Probes of Signal Transducers
    8) References

  6. "Signal-Transmission Pathways in Mast Cell Exocytosis"(Ronit Sagi-Eisenberg)
    1) Mast Cells as a Model System for the Study of Exocytosis
    2) Mast Cell Secretagogues
    3) Mast Cell Activation
       ・Role of Phosphatidylinositol (P1) Hydrolysis in Exocytosis

  7. "Ultrastructural Analysis of Anaphylactic and Piecemeal Degranulation
     of Human Mast Cells and Basophils"(Ann M. Dvorak)
    1) Introduction
    2) HUman Basophils
       ・General Ultrastructural Anatomy
       ・Piecemeal Degranulation
       ・Anaphylactic Degranulation
    3) Human Mast Cells
       ・General Ultrastructural Anatomy
       ・Piecemeal Degranulation
       ・Anaphylactic Degranulation
    4) Summary
    5) Acknowledgements
    6) References

  8. "Mast Cell-Derived Mediators"(Rauno J. Harvima and Lawrence B. Schwartz)
    1) Introduction
    2) Mediators Derived from Mast Cells and Basophils
       ・Preformed Granule-associated Mediators
       ・Newly Generated Lipid Mediator Synthesized from Arachidomic Acid
       ・Cytokines
    3) Mediators as Clinical Indicators of Mast Cell and Basophil Involvement in Disease
    4) References

  9. "Drugs Modifying the Responses of Mast Cells and Basophils"
                (Yoshimichi Okayama and Martin K. Church)
    1) Introduction
    2) Dispersal and Purification of Mast Cells and Assessment of Mediator Release
    3) Sodium Cromoglycate and Nedocromil Sodium
       ・Possible Mechanisms of Action of SCG and Nedocromil
    4) β-Adreoceptor Agonists
    5) Methylxanithines
    6) Antihistamines
    7) Conclusion
    8) References

  10. "Cutaneous Basophil Hypersensitivity - A Twenty-Year Perspective, 1970 to 1990"
                      (Ann M. Dvorak and Harold F. Dvorak)
    1) Introduction
    2) Historicak Perspective
    3) Difference between Cutaneous Basophil Hypersensitivity
    and Delayed Hypersensitivity
    4) Basophil Tissue Infiltration in Multiple Species, Organs, Diseases and Circumstances
    5) Lack of Specificity of the Majority of Basophils in CBH for Sensitizing Antigen
    6) Regular Passive Transfer of CBH by Appropriately Sensitized Lymph Node Cells
    7) Important Interactions between Basophils and Lymphocytes in CGH
       ・Induction of CGH
       ・Cytokins that Affect Basophil Function
    8) Criteria for Morphological Identification of Basophils
    in Multiple Mammalian Species
    9) PMD is a Basophil Release Reaction Uniquely Present
    in CGH and Tissue Basophils in View
    10) Summary
    11) Acknowledgements
    12) References

  11. "Mast Cells and the Lung"(C. P. Page and E. Minshall)
    1) Introduction
    2) Evidence for Mast Cell Activation in Asthma
    3) Histamine
    4) Prostaglation D2
    5) Lipoxygenase Metabolites of Arachidonic Acid Metabolism
    6) Platelet Activating Factor
    7) Proteoglycans
    8) Neutral Proteases
    9) Cytokins
    10) Mast Cell Involvement in Asthma
    11) References

  12. "Mast Cells in the Gastrointestinal Tract"(H. R. P. Miller)
    1) Introduction and Historical Perspective
    2) Mast Cell Heterogeneity
       ・Biochemistry and Histochemistry of Granule Glycosaminoglycans
       ・Heterogeneity of Granule Protease Expression
       ・Heterogeneity amongst Isolated Intestinal Mast Cell Subpopulations
         : Comparison with BMMCs
    3) Signals that Recruit INtestinal Mast Cells
       ・In View Analysis
       ・In View Characterization of Factors Controlling Mast Cell Growth
    4) Physiological Role of Gastrointestinal Mast Cells
    5) Gastrointestinal Mast Cells in Disease
       ・Helminthiasis
       ・Enteric and Syntemic Anaphylaxis
       ・Clinical Disease of the GI Tract
    6) Conclusions
    7) References

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